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GPER1 Recombinant Rabbit mAb (bsm-63809R)  
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25ul/800.00元
50ul/1400.00元
100ul/2500.00元
大包装/询价
产品编号 bsm-63809R
英文名称 GPER1 Recombinant Rabbit mAb
中文名称
别    名 CEPR; CMKRL2; DRY12; FEG-1; GPCR-Br; GPER; GPR30; LERGU; LERGU2; LyGPR; mER; 6330420K13Rik; Ceprl; GPR41; GPER1_HUMAN; GPER1; Chemoattractant receptor-like 2; Flow-induced endothelial G-protein coupled receptor 1 (FEG-1); G protein-coupled estrogen receptor 1; G-protein coupled receptor 30; IL8-related receptor DRY12; Lymphocyte-derived G-protein coupled receptor (LYGPR); Membrane estrogen receptor (mER); GPER1_MOUSE; GPER1_RAT; G-protein coupled receptor 41; G protein-coupled receptor 30; G-protein coupled estrogen receptor 1; Flow-induced endothelial G-protein coupled receptor 1; Lymphocyte-derived G-protein coupled receptor; Membrane estrogen receptor  
抗体来源 Rabbit
克隆类型 Recombinant
克 隆 号 10G9
交叉反应 Human,Mouse,Rat
产品应用 WB=1:2000-10000,IHC-P=1:1000-5000,IHC-F=1:1000-5000,IF=1:200-1000,ELISA=1:5000-20000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
PubMed PubMed
产品介绍 This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized. [provided by RefSeq, Jul 2008],

SWISS:
Q99527

Gene ID:
2852

GPR30是一种膜性雌激素蛋白受体又称非基因型雌激素膜性受体GPR30。GPR30受体广泛表达于海马、下丘脑、子宫、卵巢、乳腺、骨和心血管等全身多个系统、器官和组织,在细胞内主要定位于细胞膜、内质网、线粒体和高尔基体。 GPER与雌激素结合, ERK、PI3K/AKT)、 cAMP等第二信使途径发挥快速非基因效应,在神经系统、生殖系统、运动系统和心血管系统中发挥重要的生理作用。
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