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TREM2 Recombinant Rabbit mAb (bsm-63849R)  
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25ul/800.00元
50ul/1400.00元
100ul/2500.00元
大包装/询价
产品编号 bsm-63849R
英文名称 TREM2 Recombinant Rabbit mAb
中文名称
别    名 AD17; PLOSL2; TREM-2; Trem2a; Trem2b; Trem2c; TREM2_HUMAN; TREM2; Triggering receptor expressed on monocytes 2; TREM2_MOUSE; triggering receptor expressed on myeloid cells 2; triggering receptor expressed on myeloid cells 2a; Triggering receptor expressed on myeloid cells 2 (TREM-2) (Triggering receptor expressed on monocytes 2)  
抗体来源 Rabbit
克隆类型 Recombinant
克 隆 号 1G9
交叉反应 Human
产品应用 WB=1:2000-10000,IHC-P=1:200-1000,IHC-F=1:200-1000,IF=1:200-1000,ELISA=1:5000-20000,IP=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
PubMed PubMed
产品介绍 triggering receptor expressed on myeloid cells 2(TREM2) Homo sapiens This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012],

SWISS:
Q9NZC2

Gene ID:
54209

TREM-2是近年来发现应用于诊断炎症性疾病的重要标记物,也是感染性疾病的预警指标,与细菌感染的严重程度相关。 TREM2属于免疫球蛋白超家族TREM,表达于白细胞的细胞膜表面受体,TREM-选择性地表达于中性粒细胞和部分单核细胞,它介导的信号传导通路在炎症的发生和级联放大中起重要作用。
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