| 产品编号 | bsm-55735R |
| 英文名称 | PER2 Recombinant Rabbit mAb |
| 中文名称 | 节律蛋白2充足兔单抗 |
| 别 名 | FASPS; FASPS1; mKIAA0347; mPer2; PER2_HUMAN; PER2; hPER2; Circadian clock protein PERIOD 2; KIAA0347; PER2_MOUSE; period circadian regulator 2; period (Drosophila) homolog 2; period homolog 2 (Drosophila); period circadian clock 2 |
| 抗体来源 | Rabbit |
| 克隆类型 | Recombinant |
| 克 隆 号 | 12B5 |
| 交叉反应 | Human,Mouse,Rat |
| 产品应用 |
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 138kDa |
| 性 状 | Liquid |
| 浓 度 | 1mg/m |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PER2 |
| 亚 型 | IgG/Kappa |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
PER2, a mammalian homologue of the Drosophila period gene, shares a 40% homology with PER1 including the protein dimerization PAS domain. PER2 is a circadian regulator that may act as a transcription factor. It behaves as a negative element in circadian transcriptional loop. PER2 does not appear to bind DNA, suggesting indirect transcriptional inhibition. Expression oscillates with a 24 hour rhythm in the suprachiasmatic nucleus (SCN) and the whole eyes. Oscillations are maintained under constant darkness and are responsive to changes of the light/dark cycles. There is a 4 hour time delay between PER1 and PER2 oscillations. The expression rhythms appear to originate from retina. SWISS: O15055 Gene ID: 8864 生物钟基因Per2与肿瘤增殖, 凋亡有着重要的关联，是机体维持正常节律所必需的基因, Per2在调节生物周期节律和器官功能方面起着重要的作用。 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
