| 产品编号 | bsm-63415R |
| 英文名称 | NRP1 | Neuropilin 1 Recombinant Rabbit mAb |
| 中文名称 | |
| 别 名 | BDCA4; CD304; NP1; NRP; VEGF165R; C530029I03; NP-1; NPN-1; Npn1; NRP1_HUMAN; NRP1; Vascular endothelial cell growth factor 165 receptor; Q5T7F3_HUMAN; NRP1_MOUSE; A5 protein; Q6PAR3_MOUSE; NRP1_RAT; neuropilin 1; Neuropilin-1; CD antigen CD304 |
| 抗体来源 | Rabbit |
| 克隆类型 | Recombinant |
| 克 隆 号 | 6H8 |
| 交叉反应 | Human |
| 产品应用 | WB=1:1000-5000,IHC-P=1:1000-4000,IHC-F=1:1000-4000,IF=1:200-1000,ELISA=1:5000-20000,IP=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 产品介绍 |
This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2011], SWISS: Q5T7F3 Gene ID: 8829 CD304是一种神经元受体，被认为表达于众多的非造血细胞上，包括神经元、内皮细胞和肿瘤细胞。在体外单核细胞和造血前体细胞衍生的CD1a+树突状细胞是CD304（BDCA-4/Neuropilin-1）。 与CD303(BDCA-2)一样，CD304(BDCA-4)抗原特异性地表达于人血液和骨髓中的浆样树突状细胞。与CD303(BDCA-2)不同的是，CD304(BDCA-4)在培养的浆样树突状细胞上表达上调，同时在培养的髓系细胞能被诱导表达。在感染的扁桃体中，CD304(BDCA-4)不仅表达于浆样树突状 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
