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AXIN1 Recombinant Rabbit mAb (bsm-63421R)  
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25ul/800.00元
50ul/1400.00元
100ul/2500.00元
大包装/询价
产品编号 bsm-63421R
英文名称 AXIN1 Recombinant Rabbit mAb
中文名称
别    名 AXIN; CMDOH; PPP1R49; AXIN1-RGS; axin-1; Fu; Kb; Ki; fused; kinky; knobbly; AXIN1_CHICK; AXIN1; Axis inhibition protein 1; AXN; AXIN1_HUMAN; Axis inhibition protein 1 (hAxin); AXIN1_MOUSE; Protein Fused; AXIN1_RAT; Axis inhibition protein 1 (rAxin); axin 1; protein phosphatase 1, regulatory subunit 49; Axin-1 (Axis inhibition protein 1) (hAxin)  
抗体来源 Rabbit
克隆类型 Recombinant
克 隆 号 3F1
交叉反应 Human,Mouse
产品应用 WB=1:2000-10000,IHC-P=1:200-1000,IHC-F=1:200-1000,IF=1:200-1000,ELISA=1:5000-20000,IP=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
PubMed PubMed
产品介绍 This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta-1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],

SWISS:
O15169

Gene ID:
8312

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