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PGS2 Recombinant Rabbit mAb (bsm-63480R)  
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25ul/800.00元
50ul/1400.00元
100ul/2500.00元
大包装/询价
产品编号 bsm-63480R
英文名称 PGS2 Recombinant Rabbit mAb
中文名称
别    名 CSCD; DSPG2; PG40; PGII; PGS2; SLRR1B; DC; PGS2_HUMAN; DCN; Bone proteoglycan II; PG-S2; PGS2_MOUSE; PGS2_RAT; Dermatan sulfate proteoglycan-II (DSPG); decorin; decorin proteoglycan; Decorin (Bone proteoglycan II) (PG-S2) (PG40)  
抗体来源 Rabbit
克隆类型 Recombinant
克 隆 号 1A9
交叉反应 Human,Mouse,Rat
产品应用 WB=1:2000-10000,IHC-P=1:200-1000,IHC-F=1:200-1000,IF=1:200-1000,ELISA=1:5000-20000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
PubMed PubMed
产品介绍 This gene encodes a member of the small leucine-rich proteoglycan family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. This protein plays a role in collagen fibril assembly. Binding of this protein to multiple cell surface receptors mediates its role in tumor suppression, including a stimulatory effect on autophagy and inflammation and an inhibitory effect on angiogenesis and tumorigenesis. This gene and the related gene biglycan are thought to be the result of a gene duplication. Mutations in this gene are associated with congenital stromal corneal dystrophy in human patients. [provided by RefSeq, Nov 2015],

SWISS:
P07585

Gene ID:
1634

核心蛋白聚糖(decorin)属高分子蛋白多糖类,为蛋白聚糖(PG)的一种,是转化生长因子β(TGFβ)的拮抗剂。Decorin在调节细胞粘附、迁移、增殖、胶原纤维形成活性调节及对TGF-β的负反馈调节中起到一定的作用。
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