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Phospho-IGF1R (Tyr1135) Recombinant Rabbit mAb (bsm-63486R)  
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25ul/800.00元
50ul/1400.00元
100ul/2500.00元
大包装/询价
产品编号 bsm-63486R
英文名称 Phospho-IGF1R (Tyr1135) Recombinant Rabbit mAb
中文名称
别    名 CD221; IGFIR; IGFR; JTK13; A330103N21Rik; D930020L01; IGF-1R; hyft; IGF-1 receptor; IGFIRC; Igfr1; IGF1R_HUMAN; IGF1R; Insulin-like growth factor I receptor (IGF-I receptor); 2.7.10.1; IGF1R_MOUSE; IGF1R_RAT; insulin like growth factor 1 receptor; insulin-like growth factor 1 receptor; IGF-I Receptor β; Insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221; [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]  
抗体来源 Rabbit
克隆类型 Recombinant
克 隆 号 7G3
交叉反应 Human,Mouse,Rat
产品应用 WB=1:2000-10000,IHC-P=1:200-1000,IHC-F=1:200-1000,IF=1:200-1000,ELISA=1:5000-20000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
PubMed PubMed
产品介绍 This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014],

SWISS:
P08069

Gene ID:
3480

IGF1 receptor 是胚胎生长发育的重要影响因子,IGF-IR参与细胞凋亡并与肿瘤细胞分化、增殖密切相关。
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