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ELNE Recombinant Rabbit mAb (bsm-63488R)  
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25ul/800.00元
50ul/1400.00元
100ul/2500.00元
大包装/询价
产品编号 bsm-63488R
英文名称 ELNE Recombinant Rabbit mAb
中文名称
别    名 ELA2; GE; HLE; HNE; NE; PMN-E; SCN1; F430011M15Rik; ELNE_HUMAN; ELANE; Bone marrow serine protease; Elastase-2; Human leukocyte elastase (HLE); Medullasin; PMN elastase; 3.4.21.37; ELNE_MOUSE; Leukocyte elastase; elastase, neutrophil expressed; elastase 2, neutrophil; neutrophil elastase; polymorphonuclear leukocyte elastase; Neutrophil elastase (Bone marrow serine protease) (Elastase-2) (Human leukocyte elastase) (HLE) (Medullasin) (PMN elastase)  
抗体来源 Rabbit
克隆类型 Recombinant
克 隆 号 9A2
交叉反应 Human,Bovine
产品应用 WB=1:2000-10000,IHC-P=1:200-1000,IHC-F=1:200-1000,IF=1:200-1000,ELISA=1:5000-20000,IP=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
PubMed PubMed
产品介绍 Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode structurally similar proteins. The encoded preproprotein is proteolytically processed to generate the active protease. Following activation, this protease hydrolyzes proteins within specialized neutrophil lysosomes, called azurophil granules, as well as proteins of the extracellular matrix. The enzyme may play a role in degenerative and inflammatory diseases through proteolysis of collagen-IV and elastin. This protein also degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. Mutations in this gene are associated with cyclic neutropenia and severe congenital neutropenia (SCN). This gene is present in a gene cluster on chromosome 19. [provided by RefSeq, Jan 2016

SWISS:
P08246

Gene ID:
1991

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