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MCP1 Recombinant Rabbit mAb (bsm-63508R)  
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25ul/800.00元
50ul/1400.00元
100ul/2500.00元
大包装/询价
产品编号 bsm-63508R
英文名称 MCP1 Recombinant Rabbit mAb
中文名称
别    名 GDCF-2; HC11; HSMCR30; MCAF; MCP-1; MCP1; SCYA2; SMC-CF; JE; Sigje; CCL2_HUMAN; CCL2; Monocyte chemoattractant protein 1; Monocyte chemotactic and activating factor (MCAF); Monocyte chemotactic protein 1 (MCP-1); Monocyte secretory protein JE; Small-inducible cytokine A2; CCL2_MOUSE; Platelet-derived growth factor-inducible protein JE; CCL2_RAT; Immediate-early serum-responsive protein JE; C-C motif chemokine ligand 2; small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je); chemokine (C-C motif) ligand 2; monocyte chemotactic protein 1, homologous to mouse Sig-je; monocyte chemoattractant protein-1; monocyte chemotactic and activating factor; small inducible cytokine subfamily A (Cys-Cys), member 2; Monocyte chemotactic protein 1  
抗体来源 Rabbit
克隆类型 Recombinant
克 隆 号 6A2
交叉反应 Human
产品应用 WB=1:1000-5000,IHC-P=1:2000-10000,IHC-F=1:2000-10000,IF=1:200-1000,ELISA=1:5000-20000,IP=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
PubMed PubMed
产品介绍 This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. Elevated expression of the encoded protein is associated with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection. [provided by RefSeq, Aug 2020]

SWISS:
P13500

Gene ID:
6347

生长因子和激素( Growth Factor and Hormones) 巨噬细胞趋化蛋白1(MCP1)具有多向性调节作用的核转录因子,它可诱导与免疫和炎症有关的多种基因转录.MCP-1免疫组化阳性信号主要位于胞浆内。 单核细胞趋化蛋白-1(monocyte chemotactic protein 1,MCP-1)又称单核细胞趋化和激活因子(monoctye chemotactic and activating factor,MCAF),属于C-C亚族(β亚族)成员。MCP-1/MCAF起初是从人髓样单核
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