| 产品编号 | bsm-63521R |
| 英文名称 | PRKACA | PKA C-alpha Recombinant Rabbit mAb |
| 中文名称 | |
| 别 名 | CAFD1; PKACA; PPNAD4; CAFD2; PKA C-beta; PKACB; PKCD; CbPKA; Cs-PKA; PKCA1; KAPCA_HUMAN; PRKACA; PKA C-alpha; 2.7.11.11; KAPCB_HUMAN; PRKACB; KAPCA_MOUSE; KAPB_MOUSE; KAPCA_RAT; protein kinase cAMP-activated catalytic subunit alpha; protein kinase, cAMP-dependent, catalytic, alpha; protein kinase, cAMP-dependent, alpha catalytic subunit; cAMP-dependent protein kinase catalytic subunit alpha |
| 抗体来源 | Rabbit |
| 克隆类型 | Recombinant |
| 克 隆 号 | 4F1 |
| 交叉反应 | Human,Mouse,Rat |
| 产品应用 | WB=1:1000-5000,IHC-P=1:2000-10000,IHC-F=1:2000-10000,IF=1:200-1000,ELISA=1:5000-20000,IP=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 产品介绍 |
This gene encodes one of the catalytic subunits of protein kinase A, which exists as a tetrameric holoenzyme with two regulatory subunits and two catalytic subunits, in its inactive form. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. cAMP-dependent phosphorylation of proteins by protein kinase A is important to many cellular processes, including differentiation, proliferation, and apoptosis. Constitutive activation of this gene caused either by somatic mutations, or genomic duplications of regions that include this gene, have been associated with hyperplasias and adenomas of the adrenal cortex and are linked to corticotropin-independent Cushing's syndrome. Altern SWISS: P22694 Gene ID: 5567 激酶和磷酸酶（Kinases and Phosphatases） 蛋白激酶 A (protein kinase A，PKA) 又称依赖于cAMP的蛋白激酶A (cyclic-AMP dependent protein kinase A)，是一种结构最简单、生化特性最清楚的蛋白激酶。 蛋白激酶A属于多功能丝氨酸和苏氨酸激酶,可使蛋白磷酸化，也可自身磷酸化。在调节细胞存活中起重要作用。 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
