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ATF6A Recombinant Rabbit mAb (bsm-63526R)  
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25ul/800.00元
50ul/1400.00元
100ul/2500.00元
大包装/询价
产品编号 bsm-63526R
英文名称 ATF6A Recombinant Rabbit mAb
中文名称
别    名 ACHM7; ATF6A; ATP6alpha; 9130025P16Rik; 9630036G24; Atf6alpha; ESTM49; ATF6A_HUMAN; ATF6; cAMP-dependent transcription factor ATF-6 alpha; Activating transcription factor 6 alpha (ATF6-alpha); activating transcription factor 6; activating transcription factor 6 alpha  
抗体来源 Rabbit
克隆类型 Recombinant
克 隆 号 9C3
交叉反应 Human,Mouse,Rat
产品应用 WB=1:1000-5000,IHC-P=1:200-1000,IHC-F=1:200-1000,IF=1:200-1000,ELISA=1:5000-20000,IP=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
PubMed PubMed
产品介绍 This gene encodes a transcription factor that activates target genes for the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Although it is a transcription factor, this protein is unusual in that it is synthesized as a transmembrane protein that is embedded in the ER. It functions as an ER stress sensor/transducer, and following ER stress-induced proteolysis, it functions as a nuclear transcription factor via a cis-acting ER stress response element (ERSE) that is present in the promoters of genes encoding ER chaperones. This protein has been identified as a survival factor for quiescent but not proliferative squamous carcinoma cells. There have been conflicting reports about the association of polymorphisms in this gene with diabetes in different populations, but another polymorphism has been associated with increased plasma cholesterol levels. This gene is also thought to be a potential therapeutic target for cystic fibrosis. [provided by RefSeq, Aug 2011],

SWISS:
P18850

Gene ID:
22926

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