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Nur77 Recombinant Rabbit mAb (bsm-63542R)  
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25ul/800.00元
50ul/1400.00元
100ul/2500.00元
大包装/询价
产品编号 bsm-63542R
英文名称 Nur77 Recombinant Rabbit mAb
中文名称
别    名 GFRP1; HMR; N10; NAK-1; NGFIB; NP10; NUR77; TR3; Gfrp; Hbr-1; Hbr1; NGFI-B; NUR77-1; NUR77-2; TIS1; NR4A1_HUMAN; NR4A1; Early response protein NAK1; Nuclear hormone receptor NUR/77 (Nur77); Orphan nuclear receptor HMR; Orphan nuclear receptor TR3; ST-59; Testicular receptor 3; NAK1; NR4A1_MOUSE; Nuclear hormone receptor NUR/77; Nuclear protein N10; NR4A1_RAT; Nerve growth factor-induced protein I-B (NGFI-B); nuclear receptor subfamily 4 group A member 1; nuclear receptor subfamily 4, group A, member 1  
抗体来源 Rabbit
克隆类型 Recombinant
克 隆 号 8C6
交叉反应 Human,Mouse,Rat
产品应用 WB=1:2000-10000,IHC-P=1:200-1000,IHC-F=1:200-1000,IF=1:200-1000,ELISA=1:5000-20000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
PubMed PubMed
产品介绍 This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011],

SWISS:
P22736

Gene ID:
3164

孤儿核受体蛋白Nur77是早期反应转录因子之一,多种刺激因子如缺氧可诱导其迅速表达,Nur77参与调控细胞增殖、存活、分化等过程。这类核受体是体内广泛分布的配体依赖性的转录因子,通过调控基因协调表达,在机体的生长发育、新陈代谢,细胞分化及体内许多生长发育过程中发挥重要作用,其功能障碍将导致一系列疾病的发生,如;癌症、糖尿病、肥胖、不孕不育等等。
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