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MRP1 Recombinant Rabbit mAb (bsm-63569R)  
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25ul/800.00元
50ul/1400.00元
100ul/2500.00元
大包装/询价
产品编号 bsm-63569R
英文名称 MRP1 Recombinant Rabbit mAb
中文名称
别    名 ABC29; ABCC; DFNA77; GS-X; MRP; MRP1; Abcc1a; Abcc1b; Mdrap; Avcc1a; MRP1_HUMAN; ABCC1; ATP-binding cassette sub-family C member 1; Glutathione-S-conjugate-translocating ATPase ABCC1; Leukotriene C(4) transporter (LTC4 transporter); 7.6.2.2; MRP1_MOUSE; MRP1_RAT; ATP binding cassette subfamily C member 1 (ABCC1 blood group); multidrug resistance associated protein 1; ATP-binding cassette, sub-family C (CFTR/MRP), member 1; ATP binding cassette subfamily C member 1; glutathione S-conjugate export pump; Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter)  
抗体来源 Rabbit
克隆类型 Recombinant
克 隆 号 3F5
交叉反应 Human,Mouse
产品应用 WB=1:2000-10000,IHC-P=1:200-1000,IHC-F=1:200-1000,IF=1:200-1000,ELISA=1:5000-20000,IP=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
PubMed PubMed
产品介绍 The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown. [provided by RefSeq, Apr 2012],

SWISS:
P33527

Gene ID:
4363

多药耐药相关蛋白1(MRP1)是MRP家族中的一个成员之一,基因的染色体位点是16p13.1,它编码分子量是170-190kDa的MRP1蛋白。 MRP1又称ABCC1主要表达在消化系统中的肝脏、结肠和胰腺组织中,常用于多种肿瘤的多药耐药机制的研究。
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