| 产品编号 | bsm-63579R |
| 英文名称 | TIMP-3 Recombinant Rabbit mAb |
| 中文名称 | |
| 别 名 | HSMRK222; K222; K222TA2; SFD; Timp-3; TIMP3_HUMAN; TIMP3; Protein MIG-5; Tissue inhibitor of metalloproteinases 3 (TIMP-3); TIMP3_MOUSE; Sun; TIMP3_RAT; TIMP metallopeptidase inhibitor 3; tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, pseudoinflammatory); Metalloproteinase inhibitor 3; Tissue inhibitor of metalloproteinases 3 |
| 抗体来源 | Rabbit |
| 克隆类型 | Recombinant |
| 克 隆 号 | 7H5 |
| 交叉反应 | Human,Mouse,Rat |
| 产品应用 | WB=1:500-2000,IHC-P=1:200-1000,IHC-F=1:200-1000,IF=1:200-1000,ELISA=1:5000-20000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 产品介绍 |
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy. [provided by RefSeq, Jul 2008], SWISS: P35625 Gene ID: 7078 合成与降解（Synthesis and Degradation） 近年来，国内外科研人员对TIMP-3的抗肿瘤作用日益被重视，学者认为：TIMP-3具有强烈促凋亡、抑制血管生成、抗肿瘤浸润作用，TIMP-3与TIMP-1、2且相互间有明显协同抗肿瘤作用 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
