| 产品编号 | bsm-63630R |
| 英文名称 | UCP2 Recombinant Rabbit mAb |
| 中文名称 | |
| 别 名 | BMIQ4; SLC25A8; UCPH; UCP2_HUMAN; UCP2; Mitochondrial uncoupling protein 2 (UCP 2); Solute carrier family 25 member 8; UCP2_RAT; uncoupling protein 2; body mass index QTL 4; body mass index quantitative trait 4; uncoupling protein 2 (mitochondrial, proton carrier); Mitochondrial uncoupling protein 2; UCP 2 |
| 抗体来源 | Rabbit |
| 克隆类型 | Recombinant |
| 克 隆 号 | 4G9 |
| 交叉反应 | Human,Mouse,Rat |
| 产品应用 | WB=1:2000-10000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:200-1000,ELISA=1:5000-20000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 产品介绍 |
Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed in many tissues, with the greatest expression in skeletal muscle. It is thought to play a role in nonshivering thermogenesis, obesity and diabetes. Chromosomal order is 5'-UCP3-UCP2-3'. [prov SWISS: P55851 Gene ID: 7351 UCP-2又称解耦联蛋白 2 (UCP2 )是 1997年发现的一种新的解偶联蛋白 ,它是线粒体内膜载体家族的一员 。与其类似物UCP1相比 ,UCP2在棕色脂肪组织中含量较低 ,但在体内分布广泛。解耦联蛋白(UCP)具有使线粒体呼吸链解耦联作用,解耦联所释放的能量以热能的形式散发。在对UCP与产热关系的研究中,发现UCP2具有调节机体能量代谢的功能,并且可能是肥胖与2型糖尿病相关联的一个重要基因。 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
