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PPAR delta Recombinant Rabbit mAb (bsm-63666R)  
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25ul/800.00元
50ul/1400.00元
100ul/2500.00元
大包装/询价
产品编号 bsm-63666R
英文名称 PPAR delta Recombinant Rabbit mAb
中文名称
别    名 FAAR; NR1C2; NUC1; NUCI; NUCII; PPARB; NUC-1; PPAR-beta; PPAR-delta; PPAR[b]; PPARdelta; Pparb/d; PPARD_HUMAN; PPARD; Nuclear hormone receptor 1 (NUC1); Nuclear receptor subfamily 1 group C member 2; Peroxisome proliferator-activated receptor beta (PPAR-beta); PPARD_MOUSE; peroxisome proliferator activated receptor delta; peroxisome proliferative activated receptor, delta; peroxisome proliferator-activated receptor delta; peroxisome proliferator activated receptor beta; PPAR Delta; Nuclear hormone receptor 1; Peroxisome proliferator-activated receptor beta  
抗体来源 Rabbit
克隆类型 Recombinant
克 隆 号 7C3
交叉反应 Human,Mouse,Rat
产品应用 WB=1:2000-10000,IHC-P=1:200-1000,IHC-F=1:200-1000,IF=1:200-1000,ELISA=1:5000-20000,IP=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
PubMed PubMed
产品介绍 peroxisome proliferator activated receptor delta(PPARD) Homo sapiens This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. The encoded protein is thought to function as an integrator of transcriptional repression and nuclear receptor signaling. It may inhibit the ligand-induced transcriptional activity of peroxisome proliferator activated receptors alpha and gamma, though evidence for this effect is inconsistent. Expression of this gene in colorectal cancer cells may be variable but is typically relatively low. Knockout studies in mice suggested a role for this protein in myelination of the corpus callosum, lipid metabolism, differentiation, and epidermal cell proliferation. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. [provided by RefSeq, Aug 2017]

SWISS:
Q03181

Gene ID:
5467

类固醇受体(Steroid Receptors) 研究人员指出该分子的功能,极可能就是阻断心血管免疫发炎反应的讯号传递过程。PPAR-delta基因是控制肌肉发展的重要基因,在增加老鼠耐力的同时还能帮助它燃烧掉脂肪,研究人员发现,对于与新陈代谢有关的各项疾病,从心脏病到肥胖症都有启发性的意义,他可以阻止脂肪沉淀在动脉壁上,进而防止动脉硬化症的发生,该蛋白参与脂肪代谢、肥胖、糖尿病、动脉硬化和癌症的发病。 在动脉硬化现象发生的早期,免疫细胞会促使血管慢性的发炎,因而造成血管不断地吸收和输送脂肪,进而导致脂肪
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