| 产品编号 | bsm-63687R |
| 英文名称 | TRAF3 Recombinant Rabbit mAb |
| 中文名称 | |
| 别 名 | CAP-1; CAP1; CD40bp; CRAF1; IIAE5; IMD132A; IMD132B; LAP1; RNF118; T-BAM; TRAFAMN; amn; TRAF3_HUMAN; TRAF3; CD40 receptor-associated factor 1 (CRAF1); CD40-binding protein (CD40BP); LMP1-associated protein 1 (LAP1); RING-type E3 ubiquitin transferase TRAF3; 2.3.2.27; TRAF3_MOUSE; TNF receptor associated factor 3; TNF receptor-associated factor 3; CD40 receptor-associated factor 1; CD40-binding protein; LMP1-associated protein 1 |
| 抗体来源 | Rabbit |
| 克隆类型 | Recombinant |
| 克 隆 号 | 2H7 |
| 交叉反应 | Human,Mouse,Rat |
| 产品应用 | WB=1:2000-10000,IHC-P=1:200-1000,IHC-F=1:200-1000,IF=1:200-1000,ELISA=1:5000-20000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 产品介绍 |
TNF receptor associated factor 3(TRAF3) Homo sapiens The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Several alternatively spliced transcript variants encoding three distinct isoforms have been reported. [provided by RefSeq, Dec 2010], SWISS: Q13114 Gene ID: 7187 TRAF3是作用最为广泛的一种TRAF蛋白，它可以与LTb R、CD40、TNFRII和LMP1结合，并介导CD30、LMP1活化NF-kB。TRAF3与CD40结合后可以挽救凋亡的B细胞， TRAF3还参与CD40在B细胞中上调CD23的作用。 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
