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Rabbit Anti-HOXB2/Gold Conjugated antibody (bs-6538R-Gold)
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说 明 书: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包装/询价
产品编号 bs-6538R-Gold
英文名称 Anti-HOXB2/Gold
中文名称 胶体金标记的同源盒蛋白B2抗体
别    名 homeo box 2H; homeo box B2; homeobox B2; Homeobox protein Hox-2.8; Homeobox protein Hox-2H; Homeobox protein Hox-B2; Hox 2 8; Hox 2H; HOX2; HOX2H; hoxb2; HXB2_HUMAN; K8; K8 home protein.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul(10nm  15nm  35nm
研究领域 肿瘤  细胞生物  染色质和核信号  转录调节因子  肿瘤细胞生物标志物  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Rat,  (predicted: Human, Mouse, Chicken, Dog, Pig, Cow, Horse, Rabbit, )
产品应用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 39kDa
性    状 Lyophilized or Liquid
浓    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HOXB2 (72-120aa)
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存条件 Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles.
产品介绍 background:
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

Function:
Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.

Subunit:
Part of the nuclear protein complex gamma-globin promoter and enhancer binding factor (gamma-PE) composed at least by SATB1 and HOXB2.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the Antp homeobox family. Proboscipedia subfamily.
Contains 1 homeobox DNA-binding domain.

Database links:

Entrez Gene: 3212 Human

Entrez Gene: 103889 Mouse

Entrez Gene: 100361765 Rat

Omim: 142967 Human

SwissProt: P14652 Human

SwissProt: P0C1T1 Mouse

Unigene: 514289 Human

Unigene: 281153 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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