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Rabbit Anti-ZNF146/PE-Cy3 Conjugated antibody (bs-6755R-PE-Cy3)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-6755R-PE-Cy3
英文名称 Anti-ZNF146/PE-Cy3
中文名称 PE-Cy3标记的锌指蛋白146抗体
别    名 Only zinc finger protein; OZF; OZF_HUMAN; Zfp146; Zinc finger protein 146; Zinc finger protein OZF; ZNF146; MGC125660; MGC125661.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  肿瘤细胞生物标志物  锌指蛋白  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, )
产品应用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 33kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZNF146
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Tissue specificity: Liver, skeletal and heart muscle, mammary cells. Very low levels in brain, lung, placenta and kidney. Strongly overexpressed in many pancreas and colorectal cancers. Increased gene copy numbers are detected in 3 of 12 tumor cell lines and 2 of 12 primary pancreatic carcinomas. Overexpresseed in 80% of colorectal cancers.

Subunit:
Binds DNA. Interacts with SUMO conjugating enzyme UBC9/UBE2I. Interacts with the telomeric protein TERF2IP.

Subcellular Location:
Nucleus.

Tissue Specificity:
Liver, skeletal and heart muscle, mammary cells. Very low levels in brain, lung, placenta and kidney. Strongly overexpressed in many pancreas and colorectal cancers. Increased gene copy numbers are detected in 3 of 12 tumor cell lines and 2 of 12 primary pancreatic carcinomas. Overexpressed in 80% of colorectal cancers.

Post-translational modifications:
Sumoylated.

Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 10 C2H2-type zinc fingers.

Database links:

Entrez Gene: 100138954 Cow

Entrez Gene: 282395 Cow

Entrez Gene: 7705 Human

Entrez Gene: 26465 Mouse

Entrez Gene: 677248 Mouse

Omim: 601505 Human

SwissProt: Q28151 Cow

SwissProt: Q15072 Human

SwissProt: Q8BQN6 Mouse

Unigene: 643436 Human

Unigene: 446516 Mouse

Unigene: 456449 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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