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Rabbit Anti-CD32/PE-Cy7 Conjugated antibody (bs-4991R-PE-Cy7)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-4991R-PE-Cy7
英文名称 Anti-CD32/PE-Cy7
中文名称 PE-Cy7标记的免疫球蛋白G Fc段受体Ⅱ抗体
别    名 CD 32; CD32 antigen; CD32A; CD32B; CD32C; CDw32; Fc gamma RII a; Fc fragment of IgG low affinity II receptor for (CD32); Fc fragment of IgG low affinity IIa receptor; Fc fragment of IgG low affinity IIa receptor for (CD32); Fc fragment of IgG low affinity IIb receptor; Fc fragment of IgG low affinity IIb receptor for (CD32) ; Fc fragment of IgG low affinity IIc receptor; Fc fragment of IgG low affinity IIc receptor for (CD32); Fc gamma receptor IIB; Fc gamma RII a; Fc gamma RII b; Fc gamma RII c; Fc gamma RIIa; Fc gamma RIIb; Fc gamma RIIc; Fc receptor, IgG, low affinity IIb; Fc-gamma RII-a; Fc-gamma RII-b; Fc-gamma RII-c; FC-gamma-RIIB; Fc-GAMMA-RIIC; Fc[g]RII; FCG 2; FCG2; FcgammaRIIC; FCGR 2; FcGR; FCGR2; FCGR2A; FCGR2A1; FCGR2B; FCGR2C; Fcgr3; Fcgr3a; FcgRII; Fcr-2; Fcr-3; FcRII a; FCRII; FcRII b; FcRII c; FcRIIC; IGFR 2; IGFR2; IgG Fc receptor II a; IgG Fc receptor II b; IgG Fc receptor II beta; IgG Fc receptor II c; IgG Fc receptor II-a; IgG Fc receptor II-b; IgG Fc receptor II-c; Immunoglobulin G Fc receptor II; Low affinity immunoglobulin gamma Fc region receptor II a; Low affinity immunoglobulin gamma Fc region receptor II; Low affinity immunoglobulin gamma Fc region receptor II b; Low affinity immunoglobulin gamma Fc region receptor II c; Low affinity immunoglobulin gamma Fc region receptor II-a; Low affinity immunoglobulin gamma Fc region receptor II-b; Low affinity immunoglobulin gamma Fc region receptor II-c; Ly-17; Ly-m20; LyM-1; Lymphocyte antigen 17; MGC23887; MGC30032.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 免疫学  干细胞  细胞膜受体  淋巴细胞  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, 
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 31kDa
性    状 Lyophilized
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CD32A + CD32B
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants. [provided by RefSeq].

Function:
Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens.

Subunit:
Isoform IIB1 interacts with measles virus N protein. N protein is released in the blood following lysis of measles infected cells. This interaction presumably block inflammatory immune response. Interacts with INPP5D/SHIP1. Interacts with FGR. Interacts with LYN.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein.

Tissue Specificity:
Is the most broadly distributed Fc-gamma-receptor. Expressed in monocyte, neutrophils, macrophages, basophils, eosinophils, Langerhans cells, B-cells, platelets cells and placenta (endothelial cells). Not detected in natural killer cells.

Post-translational modifications:
Phosphorylated by SRC-type Tyr-kinases such as LYN, BLK, FYN, HCK and SYK.

Similarity:
Contains 2 Ig-like C2-type (immunoglobulin-like) domains.

Database links:

Entrez Gene: 2212 Human

Entrez Gene: 2213 Human

Entrez Gene: 9103 Human

Omim: 146790 Human

Omim: 604590 Human

Omim: 612169 Human

SwissProt: P12318 Human

SwissProt: P31994 Human

SwissProt: P31995 Human

Unigene: 352642 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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