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Rabbit Anti-C9orf86/Gold Conjugated antibody (bs-9545R-Gold)
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说 明 书: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包装/询价
产品编号 bs-9545R-Gold
英文名称 Rabbit Anti-C9orf86/Gold Conjugated antibody
中文名称 胶体金标记的9号染色体开放阅读框86抗体
别    名 Chromosome 9 open reading frame 86; FLJ10101; Hypothetical protein LOC55684; KIAA1984; Parf; Partner of ARF; pp8875; Putative GTP binding protein Parf; Rab like GTP binding protein 1; Rab like GTP binding protein 1C; Rab like protein 1; RBEL1; RP11-216L13.9.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul(10nm  15nm  35nm
研究领域 肿瘤  细胞生物  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, )
产品应用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 80kDa
性    状 Lyophilized or Liquid
浓    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human C9orf86
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存条件 Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles.
产品介绍 background:
C9orf86 (Partner of ARF;PARF) binds p19(ARF), but not the p16(INK4A) isoform of CDKN2A. Knockdown of C9orf86 by RNA interference reduced the growth inhibitory activity of p19(ARF) and enhanced the rate of cell proliferation.

Function:
May enhance cellular proliferation. May reduce growth inhibitory activity of CDKN2A.

Subcellular Location:
Cytoplasmic and Nuclear. Note=Predominantly cytoplasmic. Proposed to shuttle between cytoplasm and nucleus.

Post-translational modifications:
Isoform 1 is O-glycosylated, while other isoforms are not.

Similarity:
Belongs to the small GTPase superfamily. Rab family.

Database links:

Entrez Gene: 55684 Human

Entrez Gene: 227624 Mouse

Entrez Gene: 227624 Rat

Omim: 610615 Human

SwissProt: Q3YEC7 Human

SwissProt: Q5U3K5 Mouse

Unigene: 370555 Human

Unigene: 29600 Mouse

Unigene: 443064 Mouse

Unigene: 17709 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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