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Rabbit Anti-BASP1/Gold Conjugated antibody (bs-8662R-Gold)
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说 明 书: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包装/询价
产品编号 bs-8662R-Gold
英文名称 Anti-BASP1/Gold
中文名称 胶体金标记的脑富含膜附着信号蛋白1抗体
别    名 BASP 1; BASP-1; BASP1 protein; Brain abundant membrane attached signal protein 1; Brain Abundant Signal Protein Membrane Attached 1; Brain Acid Soluble Protein 1; CAP 23; CAP23; MGC8555; NAP 22; NAP-22; NAP22; Neuronal axonal membrane protein NAP 22; Neuronal tissue enriched acidic protein; 22 kDa neuronal tissue enriched acidic protein; BASP1_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul(10nm  15nm  35nm
研究领域 细胞生物  神经生物学  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat,  (predicted: Chicken, Dog, Pig, Cow, Horse, Rabbit, )
产品应用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 25kDa
性    状 Lyophilized or Liquid
浓    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human BASP1/Nap22
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存条件 Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles.
产品介绍 background:
Neuronal axonal membrane protein Nap-22, also designated neuronal tissue-enriched acidic protein or brain acid soluble protein (BASP1), is a Ca2+-dependent calmodulin-binding protein that is important for neuronal sprouting and plasticity. Nap-22 is abundant in brain nerve terminals and is also present in significant amounts in kidney, testis and lymphoid tissue. Nap-22 undergoes N-terminal myristoylation for membrane localization. It has been characterized as a major protein of neuronal rafts, which are known to preferentially bind membranes containing cholesterol. Nap-22 is a crucial protein active in neurite outgrowth and synaptic plasticity.

Function:
BASP1 is a brain abundant membrane bound protein with several transient phosphorylation sites and PEST motifs. BASP1 binds calmodulin, is phosphorylated by protein kinase C and undergoes N-terminal myristoylation. BASP1 is expressed specifically in nervous tissue. Intercellular signaling and nerve outgrowth are influenced by a number of proteins expressed at nerve endings and synapses of which BASP1 is one.

Subcellular Location:
Cell membrane; Lipid-anchor. Cell projection, growth cone. Note=Associated with the membranes of growth cones that form the tips of elongating axons.

Tissue Specificity:
Brain

Similarity:
Belongs to the BASP1 family.

Database links:

Entrez Gene: 10409 Human

Entrez Gene: 70350 Mouse

Omim: 605940 Human

SwissProt: P80723 Human

SwissProt: Q91XV3 Mouse

Unigene: 201641 Human

Unigene: 29586 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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