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Rabbit Anti-KLC1/PE Conjugated antibody (bs-11212R-PE)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-11212R-PE
英文名称 Rabbit Anti-KLC1/PE Conjugated antibody
中文名称 PE标记的驱动蛋白2抗体
别    名 Kinesin 2 60/70kDa; Kinesin light chain 1; Kinesin2; Kinesin-2; KLC 1; KLC; KLC1; KLC1_HUMAN; KNS 2; KNS 2A; KNS2; KNS2A; Medulloblastoma antigen MU MB 2.50; MGC15245.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 神经生物学  信号转导  细胞骨架  细胞外基质  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Chicken, Cow, Horse, Rabbit, Zebrafish, Sheep, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 65kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KLC1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The kinesin family of motor proteins comprise at least two forms of conventional kinesin (kinesin-I). They are encoded by different genes and designated ubiquitous kinesin, which is expressed in all cells and tissues, and neuronal kinesin, which is expressed exclusively in neuronal cells. Conventional kinesin is a heterotetramer of two kinesin heavy chain subunits and two kinesin light chain subunits. While the kinesin heavy chain contains motor activity, evidence suggests that the kinesin light chain is involved in either modulation of kinesin heavy chain activity or in cargo binding. The motor protein kinesin is a heterotetramer composed of two heavy chains and two light chains. Kinesin motor activity is dependent on the presence of ATP and microtubules.

Function:
Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity.

Subunit:
Belongs to the kinesin light chain family. Contains 6 TPR repeats.

Subcellular Location:
Cytoplasm; cytoskeleton.

Tissue Specificity:
Found in a variety of tissues. Mostly abundant in brain and spine.

Post-translational modifications:
Isoform I is phosphorylated on Ser-600. Isoform J is phosphorylated on Ser-631.

Similarity:
Belongs to the kinesin light chain family.
Contains 6 TPR repeats.

Database links:

Entrez Gene: 3831 Human

Entrez Gene: 16593 Mouse

Entrez Gene: 171041 Rat

Omim: 600025 Human

SwissProt: Q07866 Human

SwissProt: O88447 Mouse

SwissProt: P37285 Rat

Unigene: 20107 Human

Unigene: 657678 Human

Unigene: 278357 Mouse

Unigene: 106230 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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