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Rabbit Anti-Fascin-3/FITC Conjugated antibody (bs-11285R-FITC)
~~~促销,代码KT240603~~~
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-11285R-FITC
英文名称1 Rabbit Anti-Fascin-3/FITC Conjugated antibody
中文名称 FITC标记的肌动蛋白结合蛋白Fascin3抗体
别    名 Fascin (testis); Fascin 3; Fascin homolog 3 actin bundling protein testicular (Strongylocentrotus purpuratus) ; Fascin homolog 3 actin bundling protein testicular; Fascin3; FSCN 3; FSCN3; MGC94950; Testis fascin; FSCN3_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 信号转导  细胞骨架  细胞外基质  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Dog, Pig, Horse, Sheep, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 57kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Fascin-3
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Cell adhesion to extracellular matrix is an important physiological stimulus for organization of the Actin-based cytoskeleton. Adhesion to the matrix glycoprotein Thrombospondin 1 triggers the sustained formation of F-Actin microspikes that contain the Actin-bundling protein Fascin. These structures are also implicated in cell migration, which may be an important function of Thrombospondin 1 in tissue remodelling and wound repair. Fascin bundles Actin microfilaments within dynamic cellular structures such as microspikes, stress fibers and membrane ruffles. Fascin could serve as a prognostic factor for abnormal ovarian epithelial pathology and could be a novel target for the treatment of ovarian cancer. Fascin, an Actin-bundling protein, identifies dendritic cells in the blood and in tissues.

Function:
Acts as an actin bundling protein (By similarity).

Subcellular Location:
Cytoplasm, cytoskeleton (By similarity).

Tissue Specificity:
Expressed in testis.

Similarity:
Belongs to the fascin family.

Database links:

Entrez Gene: 29999 Human

Entrez Gene: 56223 Mouse

SwissProt: Q9NQT6 Human

SwissProt: Q9QXW4 Mouse

Unigene: 712692 Human

Unigene: 31708 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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