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Rabbit Anti-SNAP23/Gold Conjugated antibody (bs-11362R-Gold)
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说 明 书: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包装/询价
产品编号 bs-11362R-Gold
英文名称 Rabbit Anti-SNAP23/Gold Conjugated antibody
中文名称 胶体金标记的突触相关蛋白23抗体
别    名 SNAP 23; SNAP-23; SNAP23; SNAP23A; SNAP23B; SNP23_HUMAN; Synaptosomal associated protein 23; Synaptosomal associated protein 23kDa; Synaptosomal associated protein; Synaptosomal-associated protein 23; Vesicle membrane fusion protein SNAP 23; Vesicle membrane fusion protein SNAP23; Vesicle-membrane fusion protein SNAP-23; HsT17016.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul(10nm  15nm  35nm
研究领域 神经生物学  细胞类型标志物  细胞膜蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, )
产品应用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 23kDa
性    状 Lyophilized or Liquid
浓    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SNAP23
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存条件 Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles.
产品介绍 background:
Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion.

Function:
Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion.

Subunit:
Homotetramer (via coiled-coil domain), also forms heterotetramers with STX4 and VAMP3. Binds simultaneously to SNAPIN and SYN4. Found in a complex with VAMP8 and STX4 in pancreas. Interacts with STX1A and STX12 (By similarity). Binds tightly to multiple syntaxins and synaptobrevins/VAMPs. Found in a complex with VAMP8 and STX1A.

Subcellular Location:
Cell membrane. Cell membrane. Cell junction > synapse > synaptosome. Mainly localized to the plasma membrane.

Tissue Specificity:
Ubiquitous. Highest levels where found in placenta.

Similarity:
Belongs to the SNAP-25 family.
Contains 2 t-SNARE coiled-coil homology domains.

Database links:

Entrez Gene: 453365 Chimpanzee

Entrez Gene: 522423 Cow

Entrez Gene: 478268 Dog

Entrez Gene: 101141000 Gorilla

Entrez Gene: 8773 Human

Entrez Gene: 20619 Mouse

Entrez Gene: 100174679 Orangutan

Entrez Gene: 64630 Rat

Omim: 602534 Human

SwissProt: O00161 Human

SwissProt: O09044 Mouse

SwissProt: O70377 Rat

Unigene: 511149 Human

Unigene: 245715 Mouse

Unigene: 14789 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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