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Rabbit Anti-RNF39/Gold Conjugated antibody (bs-11393R-Gold)
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说 明 书: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包装/询价
产品编号 bs-11393R-Gold
英文名称 Anti-RNF39/Gold
中文名称 胶体金标记的环指蛋白39抗体
别    名 HZF; HZFW; HZFW1; LIRF; Protein HZFw; RING finger protein 39; Rnf39; RNF39_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul(10nm  15nm  35nm
研究领域 细胞生物  神经生物学  信号转导  环指蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse,  (predicted: Human, Rat, Dog, Monkey, )
产品应用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 38/45kDa
性    状 Lyophilized or Liquid
浓    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RNF39
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存条件 Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles.
产品介绍 background:
The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF39 (RING finger protein 39), also known as HZFW, HZF or LIRF, is a 420 amino acid protein that localizes to the cytoplasm and contains one RING-type zinc finger and one SPRY domain. Expressed in testis, RNF39 is thought to play a role in maintaining prolonged LTP (long term-potentiation, or the process by which synaptic strength continues to increases following chemical stimulation). Via its ability to influence the length of the LTP response, RNF39 functions to regulate early synaptic plasticity. Multiple isoforms of RNF39 exist due to alternative splicing events.

Function:
May play a role in prolonged long term-potentiation (LTP) maintenance.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Expressed in testis.

Similarity:
Contains 1 B30.2/SPRY domain.
Contains 1 RING-type zinc finger.

Database links:

Entrez Gene: 80352 Human

Entrez Gene: 171387 Rat

Omim: 607524 Human

SwissProt: Q9H2S5 Human

SwissProt: Q920M2 Rat

Unigene: 121178 Human

Unigene: 144662 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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