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Rabbit Anti-TNFSF4/Gold Conjugated antibody (bs-2463R-Gold) ~~~促销,代码KX240301~~~
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说 明 书: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包装/询价
产品编号 bs-2463R-Gold
英文名称 Anti-TNFSF4/Gold
中文名称 胶体金标记的肿瘤坏死因子配体超家族成员4抗体
别    名 CD 134L; CD 252; CD134; CD134 ligand; CD134L; CD252; CD252 antigen; glycoprotein 34 kd; Glycoprotein Gp34; GP34; OX-40L; OX40 antigen ligand; OX40 ligand; OX40L; TAX transcriptionally-activated glycoprotein 1; TNFL4_RAT; Tnfsf4; Tumor necrosis factor (ligand) superfamily member 4; Tumor necrosis factor ligand superfamily member 4; TXGP1.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul(10nm  15nm  35nm
研究领域 细胞生物  免疫学  细胞表面分子  淋巴细胞  t-淋巴细胞  细胞因子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Mouse, Rat, )
产品应用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 22kDa
性    状 Lyophilized or Liquid
浓    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from rat TNFSF4
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存条件 Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles.
产品介绍 background:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq]

Function:
Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production.

Subunit:
Homotrimer (Probable).

Subcellular Location:
Membrane; Single-pass type II membrane protein.

Tissue Specificity:
Detected in T-cell lines, but not in a macrophage cell line.

Similarity:
Belongs to the tumor necrosis factor family.

Database links:

Entrez Gene: 7292 Human

Entrez Gene: 22164 Mouse

Entrez Gene: 89814 Rat

Omim: 603594 Human

SwissProt: P23510 Human

SwissProt: P43488 Mouse

SwissProt: Q9Z2P3 Rat

Unigene: 181097 Human

Unigene: 4994 Mouse

Unigene: 30043 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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