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Rabbit Anti-LTB4-R2/Cy3 Conjugated antibody (bs-2655R-Cy3)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-2655R-Cy3
英文名称 Anti-LTB4-R2/Cy3
中文名称 Cy3标记的白三烯B4受体2抗体
别    名 BLT2R; JULF2; Leukotriene B4 receptor 2; Leukotriene B4 receptor BLT2; LT4R2_HUMAN; LTB4 receptor JULF2; LTB4-R 2; LTB4-R2; LTB4R2; Seven transmembrane receptor BLTR2.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  心血管  免疫学  信号转导  脂蛋白  新陈代谢  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Guinea Pig, )
产品应用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 41kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LTB4-R2 N-terminus
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3.

Function:
Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Widely expressed.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:

Entrez Gene: 56413 Human

Entrez Gene: 57260 Mouse

Omim: 605773 Human

SwissProt: Q9NPC1 Human

SwissProt: Q9JJL9 Mouse

Unigene: 642693 Human

Unigene: 657595 Human

Unigene: 159670 Mouse

Unigene: 485286 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

白三烯B4受体2是白三烯B4受体的新亚型,在炎症、免疫系统疾病和变态反应、包括一些肿瘤中发挥着重要作用。
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