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Rabbit Anti-Phospho-delta Opioid Receptor (Ser363)/PE Conjugated antibody (bs-3712R-PE)
~~~促销,代码KX240301~~~
~~~促销,代码KX240302~~~
订购热线:400-901-9800
订购邮箱:sales@bioss.com.cn
订购QQ:  400-901-9800
技术支持:techsupport@bioss.com.cn
说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-3712R-PE
英文名称 Anti-Phospho-delta Opioid Receptor (Ser363)/PE
中文名称 PE标记的磷酸化D型阿片受体抗体
别    名 Delta Opioid Receptor (phospho S363); p-Delta Opioid Receptor (phospho S363); Delta Opioid Receptor (phospho S363); Delta Opioid Receptor (p-S363); Delta Opioid Receptor (phospho Ser363); Delta type opioid receptor; Delta type opioid receptor DOR 1; DOR 1; DOR1; mDOR; Nbor; Opioid receptor delta 1; OPRD; OPRD1; OPRD_HUMAN; Delta-type opioid receptor; D-OR-1; DOR-1.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
产品类型 磷酸化抗体 
研究领域 免疫学  神经生物学  信号转导  转录调节因子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse,  (predicted: Rat, Chicken, Cow, Rabbit, )
产品应用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 40 kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human delta Opioid Receptor around the phosphorylation site of Ser363 [TP(p-S)DG]
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The opioid receptors are G-protein coupled, seven-transmembrane domain receptors for enkephalins, endorphins, and dynorphins. Three different opioid receptor subtypes (kappa , delta, and mu) were first identified by their different selectivities for various naturally occurring alkaloid opioid ligands, and subsequently confirmed by molecular cloning. The amino acid sequences of the opioid receptor subtypes are ~70% homologous, and are similar to somatostatin receptors (SSTRs) showing ~40 % homology with SSTR1. G-protein binding is thought to occur at the third intracellular loop of the opioid receptors, which is also the location of consensus sequences for phosphorylation of the receptor. Interestingly, the genes encoding the specific receptor subtypes are found on different chromosomes in both the human and mouse genomes.

Function:
Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Highly stereoselective. receptor for enkephalins.

Subunit:
Interacts with GPRASP1.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:

Entrez Gene: 4985 Human

Entrez Gene: 18386 Mouse

Omim: 165195 Human

SwissProt: P41143 Human

SwissProt: P32300 Mouse

Unigene: 372 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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