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Rabbit Anti-Mammaglobin B/BF488 Conjugated antibody (bs-3803R-BF488)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-3803R-BF488
英文名称 Rabbit Anti-Mammaglobin B/BF488 Conjugated antibody
中文名称 BF488标记的乳腺珠蛋白2抗体
别    名 Lipophilin C; LPHC; Mammaglobin 2; MGB2; MGC71973; SCGB2A1; Secretoglobin, family 2A, member 1; UGB3.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  免疫学  结合蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Rat, Horse, )
产品应用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 8.5kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Mammaglobin B
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Mammaglobin B may bind androgens and other steroids, it may also bind estramustine, a chemotherapeutic agent used for prostate cancer. It may be under transcriptional regulation of steroid hormones.

Subunit:
Heterodimer of a lipophilin A and a lipophilin C (mammaglobin B) monomer associated head to head.

Tissue Specificity:
Expressed in thymus, trachea, kidney, steroid responsive tissues (prostate, testis, uterus, breast and ovary) and salivary gland.

Similarity:
Belongs to the secretoglobin family. Lipophilin subfamily.

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

乳腺球蛋白是一个乳腺相关糖蛋白,它是一个分泌素家族(包括子宫球蛋白和lipophilin)成员的远亲。与其他分泌素家族成员不同,乳腺球蛋白的mRNA在乳腺组织中特异表达。在石蜡组织切片的检测中,该抗体检测乳腺癌组织中的乳腺珠蛋白敏感度高达80%。当和其他乳腺特异标记如GCDFP-15联合应用时,检测乳腺珠蛋白敏感度高达84%。有资料表明检测乳腺球蛋白,在鉴定原发癌是否发生转移中起到至关重要的作用。
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