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Rabbit Anti-intestinal FABP/PE-Cy5.5 Conjugated antibody (bs-0788R-PE-Cy5.5)
~~~促销,代码KT240603~~~
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-0788R-PE-Cy5.5
英文名称1 Rabbit Anti-intestinal FABP/PE-Cy5.5 Conjugated antibody
中文名称 PE-Cy5.5标记的肠型脂肪酸结合蛋白抗体
别    名 FABP 2; FABP2; FABPI; Fatty acid binding protein 2 intestinal; Fatty acid binding protein intestinal; Fatty acid-binding protein; I-FABP; IFABP; Intestinal fatty acid binding protein 2; MGC133132; FABPI_HUMAN.   
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 心血管  细胞生物  免疫学  生长因子和激素  糖尿病  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse,  (predicted: Rat, Chicken, Dog, Pig, Rabbit, )
产品应用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 15kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from IFABP
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Intestinal FABP is an intestinal marker. It is expressed in the small intestine. Expression in the mucosal cells of the ileum extends from the midvillar region to the villus tips. It is thought to play a role in the intracellular transport of long chain fatty acids and their acyl CoA esters and may be involved in triglyceride rich lipoprotein synthesis.

Function:
FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Expressed in the small intestine and at much lower levels in the large intestine. Highest expression levels in the jejunum.

Similarity:
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

Database links:

Entrez Gene: 2169 Human

Entrez Gene: 14079 Mouse

Entrez Gene: 25598 Rat

Omim: 134640 Human

SwissProt: P12104 Human

SwissProt: P55050 Mouse

SwissProt: P02693 Rat

Unigene: 282265 Human

Unigene: 28398 Mouse

Unigene: 91358 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Fabp2脂肪酸结合蛋白-2,参与脂肪酸代谢、运输、消化,该蛋白的异常增高使人的新陈代谢功能异常,影响人体消耗摄入的糖分,从而导致引发糖尿病的发生。FABP2多态性可能与2型糖尿病合并冠心病的胰岛素抵抗相关联。
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