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Rabbit Anti-GGT1/Gold Conjugated antibody (bs-2976R-Gold)
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说 明 书: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包装/询价
产品编号 bs-2976R-Gold
英文名称1 Rabbit Anti-GGT1/Gold Conjugated antibody
中文名称 胶体金标记的γ谷氨酰转移酶抗体
别    名 CD224; Gamma glutamyl transpeptidase; Gamma glutamyltransferase 1; Gamma glutamyltranspeptidase 1; Gamma-glutamyltransferase 1; Gamma-glutamyltranspeptidase 1 light chain; GGT 1; GGT; GGT1; GGT1_HUMAN; Glutamyl transpeptidase; GTG.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul(10nm  15nm  35nm
研究领域 细胞生物  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human,  (predicted: Mouse, Rat, )
产品应用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 61kDa
性    状 Lyophilized or Liquid
浓    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GGT1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存条件 Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles.
产品介绍 background:
Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracelular GSH level. It is part of the cell antioxidant defense mechanism. Catalyzes the transfer of the glutamyl moiety of glutathione to amino acids and dipeptide acceptors. Alternatively, glutathione can be hydrolyzed to give Cys-Gly and gamma glutamate. Isoform 3 seems to be inactive.
Tissue specificity: Detected in fetal and adult kidney and liver, adult pancreas, stomach, intestine, placenta and lung. Isoform 3 is lung-specific. There are several other tissue-specific forms that arise from alternative promoter usage but that produce the same protein.

Subunit:
Heterodimer composed of the light and heavy chains. The active site is located in the light chain.

Subcellular Location:
Membrane; Single-pass type II membrane protein.

Tissue Specificity:
Detected in fetal and adult kidney and liver, adult pancreas, stomach, intestine, placenta and lung. Isoform 3 is lung-specific. There are several other tissue-specific forms that arise from alternative promoter usage but that produce the same protein.

Similarity:
Belongs to the gamma-glutamyltransferase family.

Database links:

Entrez Gene: 2678 Human

Entrez Gene: 14598 Mouse

Entrez Gene: 397095 Pig

Entrez Gene: 116568 Rat

Omim: 612346 Human

SwissProt: P19440 Human

SwissProt: Q60928 Mouse

SwissProt: P20735 Pig

SwissProt: P07314 Rat

Unigene: 595809 Human

Unigene: 645535 Human

Unigene: 4559 Mouse

Unigene: 10010 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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