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Rabbit Anti-RIP5/AF594 Conjugated antibody (bs-7597R-AF594)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-7597R-AF594
英文名称 Anti-RIP5/AF594
中文名称 AF594标记的受体结合丝氨酸苏氨酸激酶5抗体
别    名 DSTYK; Dusty PK; Dusty protein kinase; HDCMD38P; KIAA0472; Receptor interacting protein 5; Receptor interacting protein kinase 5; Receptor interacting serine/threonine protein kinase 5; RIP homologous kinase; RIP5; SGK496; Sugen kinase 496; DUSTY_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  信号转导  细胞凋亡  转录调节因子  激酶和磷酸酶  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 105kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RIP5/RIPK5 (556-595aa)
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The RIPK5 gene encodes a dual serine/threonine and tyrosine protein kinase that is expressed in multiple tissues. Multiple alternatively spliced transcript variants have been found, but the biological validity of some variants has not been determined.

Function:
May induce both caspase-dependent apoptosis and caspase-independent cell death.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Predominantly expressed in skeletal muscle and testis. Weakly expressed in heart, brain, placenta, kidney, pancreas, spleen, thymus, prostate, uterus, small intestine, white blood cells, stomach, spinal cord and adrenal gland. Is widely distributed in the CNS. Also detected in several tumor cell lines.

Similarity:
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Contains 1 protein kinase domain.

Database links:
UniProtKB/Swiss-Prot: Q6XUX3.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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