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Rabbit Anti-Myelin Protein Zero/Cy3 Conjugated antibody (bs-0337R-Cy3)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-0337R-Cy3
英文名称 Anti-Myelin Protein Zero/Cy3
中文名称 Cy3标记的外周髓磷脂P0蛋白/P0蛋白抗体
别    名 peripheral myelin prothein Zero; MPZ; MPP; Myelin P0 protein; CHM; CMT1; CMT1B; DSS; MYELIN GLYCOPROTEIN P-ZERO; MYELIN PROTEIN PERIPHERAL; Myelin protein zero; P0; MYP0_HUMAN.   
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 神经生物学  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse, Dog,  (predicted: Human, Rat, Pig, Cow, Horse, Rabbit, Guinea Pig, )
产品应用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 24kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human P0 protein (209-228aa)
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Myelin protein-zero is the major structural protein of peripheral myelin, accounting for more than 50% of the protein present in the sheath of peripheral nerves. Expression of the gene encoding Myelin protein-zero (MPZ) is restricted to Schwann cells; MPZ is not found in the CNS. An integral membrane glycoprotein of ~28kDa, Myelin protein-zero is thought to link adjacent lamellae and thereby stabilize the myelin assembly. The other 3 major components of myelin are myelin basic protein, myelin proteolipid protein and myelin-associated glycoprotein.

Subunit:
Homodimer and homotetramer.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein.

Tissue Specificity:
Found only in peripheral nervous system Schwann cells.

Similarity:
Belongs to the myelin P0 protein family.
Contains 1 Ig-like V-type (immunoglobulin-like) domain.

Database links:

Entrez Gene: 4359 Human

Entrez Gene: 17528 Mouse

Omim: 159440 Human

SwissProt: P25189 Human

SwissProt: P27573 Mouse

 Unigene: 591486 Human

Unigene: 93883 Human

Unigene: 9986 Mouse

 UniProtKB/Swiss-Prot: P25189.1




Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

成熟的周围神经系统髓鞘主要的蛋白为P0蛋白,分子量28KDa,它具有单个跨膜区,是IgG超家族的成员之一。
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