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Rabbit Anti-BRPF3/HRP Conjugated antibody (bs-8429R-HRP)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-8429R-HRP
英文名称 Rabbit Anti-BRPF3/HRP Conjugated antibody
中文名称 辣根过氧化物酶标记的BRPF3蛋白抗体
别    名 BRPF3; BRPF 3; BRPF-3; Bromodomain and PHD finger containing protein 3; KIAA1286; BRPF3_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse, Rat,  (predicted: Human, Dog, Pig, Cow, Rabbit, Sheep, )
产品应用 WB=1:500-2000 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 136kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human BRPF3
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
BRPF3 is a 1,205 amino acid protein that forms a complex with MORF, MOZ, ING5, MEAF6 and BRPF. BRPF3 contains one bromo domain, a PHD-type zinc finger and a single PWWP domain. The gene encoding BRPF3 maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.

Function:
Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.

Subunit:
Component of the MOZ/MORF complex composed at least of ING5, KAT6A, KAT6B, MEAF6 and one of BRPF1, BRD1/BRPF2 and BRPF3.

Similarity:
Contains 1 bromo domain.
Contains 1 PHD-type zinc finger.
Contains 1 PWWP domain.

Database links:

Entrez Gene: 27154 Human

Entrez Gene: 268936 Mouse

Entrez Gene: 309647 Rat

GenBank: NM_015695.1 Human

SwissProt: Q9ULD4 Human

Unigene: 291877 Mouse

Unigene: 214091 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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