扫码关注公众号           扫码咨询技术支持           扫码咨询技术服务
  
客服热线:400-901-9800  客服QQ:4009019800  技术答疑  技术支持  质量反馈  人才招聘  关于我们  联系我们
产品中心-北京博奥森生物技术有限公司
首页 > 产品中心 > 标记一抗 > 产品信息
Rabbit Anti-TGF beta 3 propeptide/Cy5 Conjugated antibody (bs-0099R-Cy5)
订购热线:400-901-9800
订购邮箱:sales@bioss.com.cn
订购QQ:  400-901-9800
技术支持:techsupport@bioss.com.cn
说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-0099R-Cy5
英文名称 Anti-TGF beta 3 propeptide/Cy5
中文名称 Cy5标记的转移生长因子β3抗体(TGFβ3)
别    名 TGF beta 3; ARVD; FLJ16571; MGC105479; MGC118722; TGF beta 3; TGF beta3; TGF-beta-3; TGF-beta 3; TGFB 3; TGFB3; TGFB3_HUMAN; transforming growth factor beta 3; Transforming growth factor beta-3.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 信号转导  干细胞  生长因子和激素  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse, Pig,  (predicted: Human, Rat, Dog, Rabbit, )
产品应用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 30/47kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TGF-beta 3 propeptide
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The TGFBeta superfamily is composed of numerous growth and differentiation factors, including transforming growth factors Beta(TGFBeta) 1,2 and 3; placental transforming growth factor (PTGFBeta);growth /differentiation factors (GDFs); mullerian inhibiting substance (MIS);bone morphogenic proteins (BMPs);glial cell line-derived neurotrophic factor (GDNF);inhibins or activins (Alpha,Beta-A, Beta-B and Beta-C),Lefty and Nodal. Members of the TGF superfamily are involved in embryonic development and adult tissue homeostasis.


Function:
Involved in embryogenesis and cell differentiation.

Subunit:
Homodimer; disulfide-linked. Interacts with ASPN.

Subcellular Location:
Secreted.

DISEASE:
Defects in TGFB3 are a cause of familial arrhythmogenic right ventricular dysplasia type 1 (ARVD1) [MIM:107970]; also known as arrhythmogenic right ventricular cardiomyopathy 1 (ARVC1). ARVD is an autosomal dominant disease characterized by partial degeneration of the myocardium of the right ventricle, electrical instability, and sudden death. It is clinically defined by electrocardiographic and angiographic criteria; pathologic findings, replacement of ventricular myocardium with fatty and fibrous elements, preferentially involve the right ventricular free wall.

Similarity:
Belongs to the TGF-beta family.

Database links:

Entrez Gene: 7043 Human

Entrez Gene: 21809 Mouse

Entrez Gene: 25717 Rat

Omim: 190230 Human

SwissProt: P10600 Human

SwissProt: P17125 Mouse

SwissProt: Q07258 Rat

Unigene: 592317 Human

Unigene: 3992 Mouse

Unigene: 7018 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

生长因子和激素( Growth Factor and Hormones)
TGF是一种多效生长因子,对上皮细胞增值有潜在抑制作用,可抑制肿瘤生长,用于许多恶性肿瘤如:胃癌、肺癌、膀胱癌、肾癌、前列腺癌、结肠癌等多种恶性肿瘤的研究。分子量:47kDa。此抗体是TGFβ3 特异性抗体,与TGF-β1和TGF-β2没有交叉反应。
版权所有 2004-2026 www.bioss.com.cn 北京博奥森生物技术有限公司
通过国际质量管理体系ISO 9001:2015 GB/T 19001-2016    认证编号: 00122Q31509R1M/1100
京ICP备05066980号-1         京公网安备110107000727号