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Rabbit Anti-PAG608/PE-Cy3 Conjugated antibody (bs-0957R-PE-Cy3)
~~~促销,代码KX240301~~~
~~~促销,代码KX240302~~~
订购热线:400-901-9800
订购邮箱:sales@bioss.com.cn
订购QQ:  400-901-9800
技术支持:techsupport@bioss.com.cn
说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-0957R-PE-Cy3
英文名称 Anti-PAG608/PE-Cy3
中文名称 PE-Cy3标记的野生型P53诱导基因1抗体
别    名 WIG-1; p53 activated gene 608; PAG608; WIG1; FLJ12296; MGC10613; OTTHUMP00000211906; OTTHUMP00000211907; p53-activated gene 608 protein; PAG 608; WIG 1; Zinc finger matrin-type protein 3; Zinc finger protein WIG-1; ZMAT3_HUMAN; p53 inducible zinc finger protein; p53 target zinc finger protein; PAG 608; WIG 1; WIG 1/PAG608 protein; FLJ31683; WIG1; Zinc finger matrin-type protein 3; WIG1; WIG1/PAG608 protein; Zinc finger matrin type 3; Zinc finger protein WIG 1; Zinc finger protein WIG1; ZMAT 3; ZMAT3.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  染色质和核信号  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Guinea Pig, )
产品应用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 32kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human WIG-1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a protein containing three zinc finger domains and a nuclear localization signal. The mRNA and the protein of this gene are upregulated by wildtype p53 and overexpression of this gene inhibits tumor cell growth, suggesting that this gene may have a role in the p53-dependent growth regulatory pathway. Alternative splicing of this gene results in two transcript variants encoding two isoforms differing in only one amino acid.

Function:
Acts as a bona fide target gene of p53/TP53. May play a role in the TP53-dependent growth regulatory pathway. May contribute to TP53-mediated apoptosis by regulation of TP53 expression and translocation to the nucleus and nucleolus.

Subunit:
Interacts with dsRNA.

Subcellular Location:
Nucleus. Nucleus, nucleolus.

Tissue Specificity:
Highly expressed in adult brain, and moderately in adult kidney and testis. Not detected in fetal brain, heart, pancreas, adrenal gland, liver or small intestine.

Similarity:
Contains 3 matrin-type zinc fingers.

Database links:

Entrez Gene: 64393 Human

Entrez Gene: 22401 Mouse

Entrez Gene: 64394 Rat

Entrez Gene: 538512 Cow

Omim: 606452 Human

SwissProt: Q0IIC4 Cow

SwissProt: Q9HA38 Human

SwissProt: O54836 Mouse

SwissProt: O08781 Rat

Unigene: 371609 Human

Unigene: 35705 Mouse

Unigene: 2925 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Tissue Specificity : Highly expressed in adult brain, and moderately in adult kidney and testis. Not detected in fetal brain, heart, pancreas, adrenal gland, liver or small intestine.
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