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Rabbit Anti-HPV16 E6 + HPV18 E6/AF488 Conjugated antibody (bs-1719R-AF488)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-1719R-AF488
英文名称 Anti-HPV16 E6 + HPV18 E6/AF488
中文名称 AF488标记的人类乳头状瘤病毒16/18 E6抗体
别    名 HPV16+HPV18 E6; HPV16/18 protein; Human Papilloma virus; E6; Human papillomavirus type 16 E6; Human papillomavirus type 18 E6; Protein E6 .   
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细菌及病毒  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, 
产品应用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 11kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 Synthetic peptide from the HPV16 E6 + HPV18 E6 conjugated to KLH
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Human Papilloma virus (HPV) is responsible for the development of type and tissue specific papilloma in the oral cavity and in the larynx. In the skin papilloma virus can cause different types of warts and in the ano-genital region it is associated with condyloma or carcinoma. HPV types 1,6 and 11 usually are associated with benign transformations of the tissues, while e.g. HPV types 16, 18 and 31 seem to be responsible for the development of some carcinoma like cervical carcinoma. The role of HPV in non-melanoic tumours of the skin is under discussion.
Protein E6 is a Transcriptional transactivator, binding double stranded DNA. It has transforming activity inactivating, with E6-AP ubiquitin-protein ligase, the human TP53/p53 tumor suppressor protein by targeting it for degradation.

Database links:

Entrez Gene: 1489079 HPV16

Entrez Gene: 1489088 HPV18



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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