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Rabbit Anti-KCNK9/PE-Cy7 Conjugated antibody (bs-5933R-PE-Cy7)
~~~促销,代码KX240301~~~
~~~促销,代码KX240302~~~
订购热线:400-901-9800
订购邮箱:sales@bioss.com.cn
订购QQ:  400-901-9800
技术支持:techsupport@bioss.com.cn
说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-5933R-PE-Cy7
英文名称 Anti-KCNK9/PE-Cy7
中文名称 PE-Cy7标记的TWIK相关酸敏感钾离子通道蛋白9抗体
别    名 KCNK 9; KCNK-9; TASK3; Potassium channel subfamily K member 9; Acid-sensitive potassium channel protein TASK-3; TWIK-related acid-sensitive K(+) channel 3; Two pore potassium channel KT3.2; Short=Two pore K(+) channel KT3.2; KCNK9_HUMAN   
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  免疫学  神经生物学  通道蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Sheep, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 40kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KCNK9
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
KCNK9 or TASK-3 (TWIK-related Acid sensitive K+ channel) is a member of the potassium channel family of proteins that contain two-pore domain and four transmembrane domains. These channels are characterized as leak K+ channels that are sensitive to changes in the extracellular pH. The physiological functions of TASK channels are largely unknown; it has been proposed that they may be involved in the regulation of breathing, aldosterone secretion and anesthetic-mediated neuronal activity. They were found to act in neurons' membrane potential and in resting K+ currents.

Function:
pH-dependent, voltage-insensitive, background potassium channel protein.

Subcellular Location:
Membrane; Multi-pass membrane protein

Tissue Specificity:
Mainly found in the cerebellum. Also found in adrenal gland, kidney and lung.

DISEASE:
Defects in KCNK9 are the cause of Birk-Barel mental retardation dysmorphism syndrome (BIBAS) [MIM:612292]. A syndrome characterized by mental retardation, hypotonia, hyperactivity, and facial dysmorphism.

Similarity:
Belongs to the two pore domain potassium channel (TC 1.A.1.8)

Database links:

Entrez Gene: 428382 Chicken

Entrez Gene: 51305 Human

Omim: 605874 Human

SwissProt: Q9NPC2 Human

Unigene: 493037 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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