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Rabbit Anti-HS6ST1/AP Conjugated antibody (bs-11854R-AP)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-11854R-AP
英文名称 Anti-HS6ST1/AP
中文名称 碱性磷酸酶(AP)标记的硫酸乙酰肝素6脑苷脂转硫酸酶1抗体
别    名 6OST 1; 6OST1; DKFZp547H098; FLJ25392; H6 ST1; H6ST 1; H6ST1_HUMAN; Heparan sulfate 6 O sulfotransferase 1; Heparan sulfate 6 sulfotransferase; Heparan sulphate 6 O sulphotransferase 1; Heparan-sulfate 6-O-sulfotransferase 1; HS6 ST1; HS6ST 1; HS6ST ; HS6ST-1; HS6ST1; MGC116899; MGC116901.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  神经生物学  信号转导  生长因子和激素  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Rabbit, )
产品应用 IHC-P=1:50-200 IHC-F=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 48kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HS6ST1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Heparan sulfate structures, which are responsible for executing multiple biologic activities, are generated and regulated by heparan sulfate (HS) biosynthetic enzymes. HS6ST1 (heparan sulfate 6-O-sulfotransferase 1), also known as HS6ST, is a 411 amino acid single-pass type II membrane protein that exists as multiple alternatively spliced isoforms and belongs to the sulfotransferase 6 family. Expressed in fetal brain, HS6ST1 functions as a 6-O-sulfation enzyme that specifically catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to the N-sulfoglucosamine residue (GlcNS) HS. HS6ST1 is subject to post-translational N-glycosylation and is encoded by a functional gene on human chromosome 2 and a pseudogene on human chromosome 1 (known as LOC728969).

Function:
6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.

Subcellular Location:
Membrane; Single-pass type II membrane protein

Tissue Specificity:
Expressed in fetal brain.

Post-translational modifications:
N-glycosylated.

Similarity:
Belongs to the sulfotransferase 6 family.

Database links:

Entrez Gene: 9394 Human

Entrez Gene: 50785 Mouse

Omim: 604846 Human

SwissProt: O60243 Human

SwissProt: Q9QYK5 Mouse

Unigene: 512841 Human

Unigene: 213566 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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