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Rabbit Anti-LBX1/AP Conjugated antibody (bs-11867R-AP)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-11867R-AP
英文名称 Rabbit Anti-LBX1/AP Conjugated antibody
中文名称 碱性磷酸酶(AP)标记的转录因子LBX1抗体
别    名 Homeobox; HPX 6; HPX6 antibodyLady bird like homeobox; Ladybird homeobox 1; Ladybird homeobox homolog 1; Ladybird homeobox protein homolog 1; LBX 1; LBX 1H; LBX1H; Transcription factor LBX1; Transcription factor similar to D. melanogaster homeodomain protein lady bird late; LBX1_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  神经生物学  信号转导  干细胞  转录调节因子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Zebrafish, )
产品应用 WB=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 30kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LBX1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The human homolog of the Drosophila lady bird late gene, LBX1, is specifically expressed in the developing central nervous system and musculoskeletal system. The LBX1 gene has a restrictive expression pattern in the dorsal portion of the mantle of the spinal cord and the hindbrain of the CNS. In the developing mouse and chicken musculoskeletal system, Lbx1 is expressed in migrating limb muscle precursor cells. In addition, Lbx1 may regulate migratory patterns of limb muscle cell precursors and may be essential to dorsal identification of forelimb muscles.

Function:
This gene and the orthologous mouse gene were found by their homology to the Drosophila lady bird early and late homeobox genes. In the mouse, this gene is a key regulator of muscle precursor cell migration and is required for the acquisition of dorsal identities of forelimb muscles.

Subunit:
Interacts with SKOR1 which acts as a transcriptional corepressor

Subcellular Location:
Nuclear

Similarity:
Contains 1 homeobox DNA-binding domain.

Database links:

Entrez Gene: 10660 Human

Entrez Gene: 16814 Mouse

Entrez Gene: 499362 Rat

Omim: 604255 Human

SwissProt: P52954 Human

SwissProt: P52955 Mouse

SwissProt: Q1XID0 Rat

Unigene: 37128 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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