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Rabbit Anti-NAV2/Gold Conjugated antibody (bs-11892R-Gold)
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说 明 书: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包装/询价
产品编号 bs-11892R-Gold
英文名称 Rabbit Anti-NAV2/Gold Conjugated antibody
中文名称 胶体金标记的维甲酸诱导神经母细胞瘤蛋白1抗体
别    名 HELAD1; Helicase, APC down regulated 1; KIAA1419; mCG 145366; mKIAA3015; NAV 2; Neuron navigator 2; POMFIL2; Pore membrane and/or filament interacting like protein 2; RAINB1; RAINB2; Retinoic acid inducible in neuroblastoma 1; Steerin 2; STEERIN2; Unc 53 homolog 2; Unc53H2; NAV2_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul(10nm  15nm  35nm
研究领域 肿瘤  细胞生物  神经生物学  肿瘤细胞生物标志物  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human,  (predicted: Mouse, Dog, Cow, Horse, Rabbit, )
产品应用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 268kDa
性    状 Lyophilized or Liquid
浓    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NAV2/RAINB1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存条件 Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles.
产品介绍 background:
This gene encodes a member of the neuron navigator gene family, which may play a role in cellular growth and migration. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Function:
NAV2 protein shows high similarity to Caenorhabditis elegans, unc-53, that is required for axonal elongation of mechanosensory neurons, suggesting that these proteins are orthologs. Thus, NAV2 may be involved in the vitamin A metabolite, atRA (all-trans retinoic acid)-mediated neurite outgrowth. NAV2 possesses 3' to 5' helicase activity and exonuclease activity and is involved in the development of different sensory organs.

Subcellular Location:
Nuclear.

Tissue Specificity:
Highly expressed in the brain, kidney and liver. Also expressed in the thyroid, mammary gland, spinal cord, heart, placenta and lung. Abundantly expressed in colon cancers.

Similarity:
Belongs to the Nav/unc-53 family.
Contains 1 CH (calponin-homology) domain.

Database links:

Entrez Gene: 89797 Human

Omim: 607026 Human

SwissProt: Q8IVL1 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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