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Rabbit Anti-CORO7/APC Conjugated antibody (bs-13999R-APC)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-13999R-APC
英文名称 Anti-CORO7/APC
中文名称 APC标记的肌动蛋白结合蛋白7抗体
别    名 Clipin-E; CORO6; CORO7_HUMAN; Coronin, actin binding protein 6; Coronin-6; Coronin-like protein E; FLJ14871; PP1009; PP1782; PP1881.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  转运蛋白  结合蛋白  细胞骨架  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Sheep, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 101kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CORO7
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Coronins, such as CORO7, constitute an evolutionarily conserved family of WD-repeat actin-binding proteins. CORO7 plays a role in Golgi complex morphology and function (Rybakin et al., 2004, 2006 [PubMed 15327992] [PubMed 16905771]).[supplied by OMIM, Mar 2008]

Function:
May play a role in the maintenance of the Golgi apparatus morphology and in the protein export from the Golgi.

Subcellular Location:
Cytoplasm > cytosol. Golgi apparatus membrane. Cytoplasmic vesicle. Predominantly cytosolic. Detected on vesicle-like cytoplasmic structures and on the cis-Golgi. Not associated with actin filaments.

Post-translational modifications:
The membrane-associated form is phosphorylated on tyrosine residues.

Similarity:
Belongs to the WD repeat coronin family.
Contains 8 WD repeats.

Database links:

Entrez Gene: 79585 Human

Entrez Gene: 78885 Mouse

Entrez Gene: 192276 Rat

Omim: 611668 Human

SwissProt: P57737 Human

SwissProt: Q9D2V7 Mouse

SwissProt: O35828 Rat

Unigene: 437957 Human

Unigene: 325512 Mouse

Unigene: 13808 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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