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Rabbit Anti-DERA/FITC Conjugated antibody (bs-14279R-FITC)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-14279R-FITC
英文名称 Anti-DERA/FITC
中文名称 FITC标记的脱氧核糖磷酸醛缩酶样抗体
别    名 Deoxyriboaldolase; 2 deoxyribose 5 phosphate aldolase homolog C. elegans; CGI 26; CGI26; CGI-26; DEOC; DEOC_HUMAN; Deoxyriboaldolase; Deoxyribose phosphate aldolase like; DERA; Phosphodeoxyriboaldolase; Putative deoxyribose phosphate aldolase; Putative deoxyribose-phosphate aldolase.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  心血管  发育生物学  新陈代谢  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 35kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DERA
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
DERA is a 318 amino acid member of the deoC/fbaB aldolase protein family. Involved in the carbohydrate degradation pathway, DERA catalyzes the conversion of 2-deoxy-D-ribose 5-phosphate to D-glyceraldehyde 3-phosphate and an acetyldehyde. The gene that encodes DERA maps to human chromosome 12, which encodes over 1,100 genes within 132 million bases, making up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster, which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy.

Function:
Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2.

Similarity:
Belongs to the deoC/fbaB aldolase family. DeoC type 2 subfamily.

Database links:

Entrez Gene: 51071 Human

SwissProt: Q9Y315 Human

Unigene: 39429 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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