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Rabbit Anti-CSDE1/BF594 Conjugated antibody (bs-14083R-BF594)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-14083R-BF594
英文名称 Rabbit Anti-CSDE1/BF594 Conjugated antibody
中文名称 BF594标记的RNA冷休克域结合蛋白E1抗体
别    名 Cold shock domain containing E1 RNA binding; Cold shock domain containing protein E1; Cold shock domain-containing protein E1; Csde1; CSDE1_HUMAN; D1S155E; DKFZp779B0247; DKFZp779J1455; FLJ26882; N-ras upstream gene protein; NRAS related; Nras upstream gene protein; NRU; Protein UNR; RP5 1000E10.3; UNR; UNR protein; Upstream of NRAS.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  转录调节因子  结合蛋白  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 89kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CSDE1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
UNR is a 798 amino acid protein that localizes to the cytoplasm and contains nine CDS (cold shock) domains. Existing as a component of the multi-protein autoregulatory ribonucleoprotein complex (ARC), UNR functions as an RNA-binding protein that is required for the initiation of rhinovirus RNA translation and is thought to be involved in translationally coupled mRNA turnover. UNR is expressed as two isoforms, designated long and short, and shares over 98% amino acid identity with its rat counterpart, suggesting a conserved role between species. The gene encoding UNR maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.

Function:
RNA-binding protein. Required for internal initiation of translation of human rhinovirus RNA. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.

Subcellular Location:
Cytoplasm.

Similarity:
Contains 9 CSD (cold-shock) domains.

Database links:

Entrez Gene: 7812 Human

Entrez Gene: 513993 Cow

Entrez Gene: 229663 Mouse

Entrez Gene: 117180 Rat

Omim: 191510 Human

SwissProt: O75534 Human

SwissProt: Q91W50 Mouse

SwissProt: P18395 Rat

Unigene: 69855 Human

Unigene: 277713 Mouse

Unigene: 3562 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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