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Rabbit Anti-FOXD1/HRP Conjugated antibody (bs-12193R-HRP)
~~~促销,代码KT240603~~~
~~~促销,代码KT240603~~~
订购热线:400-901-9800
订购邮箱:sales@bioss.com.cn
订购QQ:  400-901-9800
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-12193R-HRP
英文名称1 Rabbit Anti-FOXD1/HRP Conjugated antibody
中文名称 辣根过氧化物酶标记的叉头蛋白D1抗体
别    名 Brain Factor 2; FKH L8; FKHL 8; FKHL8; Forkhead (Drosophila) like 8; Forkhead box D1; Forkhead box protein D1; Forkhead drosophila homolog like 8; Forkhead like 8; Forkhead related activator 4; Forkhead related protein FKHL8; Forkhead related transcription factor 4; Forkhead-related protein FKHL8; Forkhead-related transcription factor 4; FOX D1; FOXD 1; foxd1; FOXD1_HUMAN; FREAC 4; FREAC-4; FREAC4.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  发育生物学  神经生物学  干细胞  转录调节因子  细胞分化  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Chicken, Dog, Rabbit, Sheep, )
产品应用 WB=1:500-2000 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 46kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from Human FOXD1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
FOXD1 is involved in regulating inflammation as well as kidney and retinal development. FOXD1 regulates the activity of NFAT and NFkB. Deficiency of FOXD1 results in multiorgan systemic inflammation, exaggerated Th cell-derived cytokine production, and T cell proliferation in autogolgous MLRs. In kidneys, FOXD1 controls the production of signals required for the normal transition of induced mesenchyme into tubular epithelium and full growth and branching of the collecting system. Deletion of FOXD1 results in renal abnormalities. FOXD2 acts as a modulator of T cell activation.

Function:
Transcription factor required for formation of positional identity in the developing retina, regionalization of the optic chiasm and morphogenesis of the kidney. Can neuralize ectodermal cells directly.

Subcellular Location:
Nucleus.

Similarity:
Contains 1 fork-head DNA-binding domain.

Database links:

Entrez Gene: 2297 Human

Entrez Gene: 15229 Mouse

GenBank: NP_004463 Human

Omim: 601091 Human

SwissProt: Q16676 Human

SwissProt: Q61345 Mouse

Unigene: 519385 Human

Unigene: 347441 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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