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Rabbit Anti-APOBEC1/Gold Conjugated antibody (bs-12492R-Gold)
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说 明 书: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包装/询价
产品编号 bs-12492R-Gold
英文名称 Rabbit Anti-APOBEC1/Gold Conjugated antibody
中文名称 胶体金标记的载脂蛋白B-mRNA编辑酶复合物1抗体
别    名 ABEC1_HUMAN; APOBEC 1; APOBEC1; Apolipoprotein B mRNA editing enzyme; Apolipoprotein B mRNA editing enzyme catalytic polypeptide 1; Apolipoprotein B mRNA editing enzyme complex 1; Apolipoprotein B mRNA-editing enzyme 1; BEDP; C->U-editing enzyme APOBEC-1; CDAR1; EC 3.5.4.; HEPR.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul(10nm  15nm  35nm
研究领域 细胞生物  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Horse, )
产品应用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 28kDa
性    状 Lyophilized or Liquid
浓    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human APOBEC1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存条件 Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles.
产品介绍 background:
Post-transcriptional editing of apolipoprotein B (apoB) mRNA is regulated by This gene encodes a member of the cytidine deaminase enzyme family. The encoded protein forms a multiple-protein editing holoenzyme with APOBEC1 complementation factor (ACF) and APOBEC1 stimulating protein (ASP). This holoenzyme is involved in the editing of C-to-U nucleotide bases in apolipoprotein B and neurofibromatosis-1 mRNAs. [provided by RefSeq, Jul 2008].

Function:
Catalytic component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in the APOB mRNA. Also involved in CGA (Arg) to UGA (Stop) editing in the NF1 mRNA.

Subunit:
Homodimer. Part of the apolipoprotein B mRNA editing complex with A1CF. Found in a complex with CELF2/CUGBP2 and A1CF. Interacts with HNRPAB and SYNCRIP.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Expressed exclusively in the small intestine.

Similarity:
Belongs to the cytidine and deoxycytidylate deaminase family.

Database links:
UniProtKB/Swiss-Prot: P41238.3

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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