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Rabbit Anti-DNAJA2/AF555 Conjugated antibody (bs-13023R-AF555)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-13023R-AF555
英文名称 Anti-DNAJA2/AF555
中文名称 AF555标记的细胞周期蛋白3抗体
别    名 Cell cycle progression 3 protein; Cell cycle progression restoration gene 3 protein; CPR 3; CPR3; Dj3; DJA 2; DJA2; DnaJ (Hsp40) homolog subfamily A member 2; DNAJ; DnaJ homolog subfamily A member 2; DNAJA 2; Dnaja2; DNJ 3; Dnj3; DNJA2_HUMAN; HIRA interacting protein 4; HIRA-interacting protein 4; HIRIP 4; HIRIP4; OTTHUMP00000164136; PRO3015; RDJ 2; RDJ2; Renal carcinoma antigen NY REN 14; Renal carcinoma antigen NY-REN-14.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  心血管  细胞生物  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse,  (predicted: Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, Monkey, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 46kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DNAJA2/CPR3
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The DnaJ family is one of the largest of all the chaperone families and has evolved with diverse cellular localization and functions. The presence of the J domain defines a protein as a member of the DnaJ family. DnaJ heat shock induced proteins are from the bacterium Escherichia coli and are under the control of the htpR regulatory protein. The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. The proteins contain cysteine rich regions that are composed of zinc fingers that form a peptide binding domain responsible for the chaperone function. DnaJ proteins are important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. DnaJA2 (DnaJ homolog subfamily A member 2), also known as HIRA-interacting protein 4 or cell cycle progression restoration gene 3 protein, contains one CR-type zinc finger and is a co-chaperone of HSC 70.

Function:
Co-chaperone of Hsc70.

Subcellular Location:
Membrane.

Similarity:
Contains 1 CR-type zinc finger.
Contains 1 J domain.

Database links:

Entrez Gene: 10294 Human

Entrez Gene: 56445 Mouse

Entrez Gene: 84026 Rat

Omim: 611322 Human

SwissProt: O60884 Human

SwissProt: Q9QYJ0 Mouse

SwissProt: O35824 Rat

Unigene: 368078 Human

Unigene: 475573 Mouse

Unigene: 3904 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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