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Rabbit Anti-Somatostatin 28/PE Conjugated antibody (bs-8877R-PE)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-8877R-PE
英文名称 Anti-Somatostatin 28/PE
中文名称 PE标记的生长抑素抗体
别    名 Growth hormone release inhibiting factor; SMS_HUMAN; SMST; SST; Somatostatin 28; Somatostatin28; Somatostatin-28; Somatostatin-28; somatostatin SS28.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  发育生物学  神经生物学  干细胞  生长因子和激素  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse, Rat,  (predicted: Human, Dog, Pig, Cow, Horse, Rabbit, )
产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 3kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Somatostatin 28
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Somatostatin is a regulatory hormone that is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to high-affinity G protein-coupled somatostatin receptors. This cyclic tetradecapeptide inhibits the secretion of many important hormones, including somatotropin (also designated growth hormone, or GH), insulin and glucagon. Somatostatin is found in both the hypothalamus and pancreas. Somatostatin is thought to be involved in the regulation of insulin synthesis. The hormone somatostatin has active 14 amino acid and 28 amino acid forms that are produced by alternate cleavage of the single preproprotein encoded by this gene. In the cerebellum, Somatostatin-14 and Somatostatin-28 are highly expressed at birth and in the adult stage, respectively. Somatostatin affects rates of neurotransmission in the central nervous system and proliferation of both normal and tumorigenic cells. The gene encoding Somatostatin maps to human chromosome 3q28.

Function:
The cyclic tetradecapeptide somatostatin is widely distributed throughout the body and is an important regulator of endocrine and nervous system function. It exerts its biologic actions by binding to specific high affinity receptors on the cell surface. Somatostatin inhibits the release of somatotropin. Somatostatin has also been shown in sympathetic nerves, mucosal cells, myenteric nerves of the gastrointestinal tract, salivary glands and in some parafollicular cells of the thyroid. Somatostatin positive cells may also be present in medullary thyroid carcinomas, C cell hyperplasia, thymic and lung tumors and pulmonary small cell carcinomas.

Subcellular Location:
Secreted.

Similarity:
Belongs to the somatostatin family.

Database links:

Entrez Gene: 396279 Chicken

Entrez Gene: 280932 Cow

Entrez Gene: 6750 Human

Entrez Gene: 20604 Mouse

Entrez Gene: 24797 Rat

Omim: 182450 Human

SwissProt: P33094 Chicken

SwissProt: P26917 Cow

SwissProt: P61278 Human

SwissProt: P60041 Mouse

SwissProt: P60042 Rat

Unigene: 12409 Human

Unigene: 34418 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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