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Rabbit Anti-HINT1/Gold Conjugated antibody (bs-10228R-Gold)
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说 明 书: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包装/询价
产品编号 bs-10228R-Gold
英文名称 Rabbit Anti-HINT1/Gold Conjugated antibody
中文名称 胶体金标记的组氨酸三聚体核苷结合蛋白1抗体
别    名 histidine triad nucleotide binding protein 1; Adenosine 5' monophosphoramidase; Adenosine 5'-monophosphoramidase; HINT 1; HINT-1; histidine triad nucleotide binding protein 1; histidine triad nucleotide binding protein; histidine triad nucleotide-binding protein; Histidine triad nucleotide-binding protein 1; PKCI 1; PKCI-1; PKCI1; PRKCNH1; Protein kinase C inhibitor 1; Protein kinase C interacting protein 1; Protein kinase C-interacting protein 1; HINT1_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul(10nm  15nm  35nm
研究领域 肿瘤  细胞生物  免疫学  结合蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, )
产品应用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 14kDa
性    状 Lyophilized or Liquid
浓    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HINT1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存条件 Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles.
产品介绍 background:
The protein encoded by this gene can hydrolyze substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester, and AMP-NH2. The encoded protein interacts with these substrates via a histidine triad motif, which is part of the loop that binds to the substrate. This gene has been found to be a tumor suppressing gene. Several transcript variants, but only one of them protein-coding, have been found for this gene. [provided by RefSeq, Dec 2012].

Function:
Hydrolyzes adenosine 5'-monophosphoramidate substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester and AMP-NH2.

Subunit:
Homodimer. Interacts with CDK7.

Subcellular Location:
Cytoplasm. Nucleus. Note=Interaction with CDK7 leads to a more nuclear localization.

Tissue Specificity:
Widely expressed.

Similarity:
Belongs to the HINT family.
Contains 1 HIT domain.

Database links:

Entrez Gene: 3094 Human

Entrez Gene: 15254 Mouse

Entrez Gene: 690660 Rat

Omim: 601314 Human

SwissProt: P49773 Human

SwissProt: P70349 Mouse

SwissProt: P62959 Rat

Unigene: 483305 Human

Unigene: 425 Mouse

Unigene: 138667 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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